Over 30% of users of fen-phen experienced serious heart valve conditions. However, one half of fen-phen, phentermine, has been found to be relatively safe. Phentermine is now being studied in combination with topiramate instead of fenfluramine. This combination drug has been found to be much safer than fen-phen and is Food and Drug Administration approved and marketed as Qsymia.
Qsymia is manufactured as an extended release medication for appetite suppression and weight loss. It was first developed by Vivus Inc., a California based pharmaceutical company. In research, statistical significance was found for moderate weight loss using this combination drug in those who are considered obese. There were also noted improvements in comorbidities that often come along with weight loss, including improved glycemia, decreased blood pressure, and improved cholesterol levels. The combination of these two drugs has shown to be quite effective and much safer than fen-phen. Phentermine is a well known appetite suppressant and stimulant. Topiramate is an anticonvulsant that has been found to promote weight loss as a side effect, making this an ideal combination for those who are suffering with obesity who are wanting to make a life change.
Qsymia was approved in 2012 by the United States Food and Drug Administration for chronic weight management. The FDA recommends that users use this combination drug in conjunction with a reduced calorie diet and increased physical activity. This is not just an easy way out in which one can take a pill and lose weight. Diet and exercise are extremely important, not only in losing weight, but also in overall health. This drug is aimed at those who are obese, not just overweight. Many people can lose weight with proper lifestyle changes including diet and exercise, but for those who are having problems losing the weight with these changes, Qsymia can be a life changer and a life saver. This drug is particularly helpful for those who are obese with common comorbidities such as hypertension, diabetes, and dyslipidemia.
This drug is only available through prescription and can be obtained at a pharmacy or through a certified mail order pharmacy network. While this combination drug has been found to be safer than fen-phen, there are some countries that have denied approval due to potential side effects. These include heart and blood vessel damage, psychiatric side effects, and cognitive side effects. This is another reason it is so important to consult a physician about any current health risks or concerns you may have when seeking out this medication for your weight loss needs. It is also not recommended for women who are pregnant, nursing, or those who may become pregnant. If you are suffering with obesity and having trouble getting and keeping the weight off, it may be worthy to consult with your physician to see if Qsymia is a safe and viable option to help you with your weight loss goals.